Contaminated Human Growth hormone as a cause of Creutzfeldt-Jakob disease.
نویسنده
چکیده
Eleven plaintiffs vs. The United Kingdom Medical Research Council (First Defendant) and the Secretary of State of Health (Second Defendant). High Court of Justice, Queen's Bench Division, No. 1994-N-06806. Judgement by Mr. Justice Morland, London; unrevised text, July 24th, 1996.
منابع مشابه
Creutzfeldt-Jakob disease: A case report
Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
متن کاملCreutzfeldt-Jakob disease with unusually extensive neuropathology in a child treated with native human growth hormone
We report a case of iatrogenic Creutzfeldt-Jakob disease(iCJD) in a child with a neonatal growth hormone (GH) deficiency that was treated with native human growth hormone (hGH) between the ages of 9 months and 7 years. Three years after the end of treatment a progressive neurological syndrome consistent with Creutzfeldt-Jakob disease (CJD) developed, leading to death within a year, at age 11. N...
متن کاملIatrogenic Creutzfeldt-Jakob Disease, Final Assessment
The era of iatrogenic Creutzfeldt-Jakob disease (CJD) has nearly closed; only occasional cases with exceptionally long incubation periods are still appearing. The principal sources of these outbreaks are contaminated growth hormone (226 cases) and dura mater grafts (228 cases) derived from human cadavers with undiagnosed CJD infections; a small number of additional cases are caused by neurosurg...
متن کاملMortality, neoplasia, and Creutzfeldt-Jakob disease in patients treated with human pituitary growth hormone in the United Kingdom.
OBJECTIVE To determine the cause of death and incidence of neoplasia in patients treated with human pituitary growth hormone. DESIGN A long term cohort study established to receive details of death certification and tumour registrations through the Office of Population Censuses and Surveys and NHS central register. PATIENTS All patients (1246 male, 662 female) treated for short stature with...
متن کاملEarly cognitive decline in Creutzfeldt-Jakob disease associated with human growth hormone treatment.
BACKGROUND Most cases of Creutzfeldt-Jakob disease (CJD) in recipients of human cadaveric growth hormone present with a cerebellar syndrome. Dementia is thought to occur late and as a minor feature of the illness. However, neuropsychology data published on these cases are largely qualitative and anecdotal. The first published case does include a neuropsychological assessment seven months after ...
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عنوان ژورنال:
- The International journal of risk & safety in medicine
دوره 9 1 شماره
صفحات -
تاریخ انتشار 1996